SCHEMBL925364

SCHEMBL925364

CCCC[Sn](CCCC)(CCCC)C1=CCCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2390664 0.89
SCHEMBL238943 0.73 NPC1 (0.33)
SCHEMBL238978 0.72
SCHEMBL1358657 0.70 ALDH1A1 (0.34)
SCHEMBL9596829 0.69 ALDH1A1 (0.33)
SCHEMBL7782028 0.68
SCHEMBL7109983 0.66
SCHEMBL623051 0.64 MAPK1 (0.35)
SCHEMBL1705145 0.63 TP53 (0.33)
SCHEMBL3875145 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114489-A1 MASKED IL12 PROTEIN TAGWORKS PHARMACEUTICALS B.V. (NL) 2025-04-10 US disclosed
EP-4372000-A2 MASKED IL12 PROTEIN Tagworks Pharmaceuticals B.V. (NL) 2024-05-22 EP disclosed
EP-4314031-B1 MASKED IL12 PROTEIN TAGWORKS PHARMACEUTICALS B V (NL) 2024-03-13 EP disclosed
EP-4314031-A1 MASKED IL12 PROTEIN Tagworks Pharmaceuticals B.V. (NL) 2024-02-07 EP disclosed
WO-2023158305-A1 MASKED IL12 PROTEIN TAGWORKS PHARMACEUTICALS B.V. (NL) 2023-08-24 WO disclosed
US-8188139-B2 Heterocyclic-substituted phenyl methanones HOFFMAN-LA ROCHE INC. (US) 2012-05-29 US disclosed
US-8163766-B2 Beta-secretase modulators and methods of use AMGEN INC. (US) 2012-04-24 US disclosed
US-20110118250-A1 BETA-SECRETASE MODULATORS AND METHODS OF USE AMGEN INC. (US) 2011-05-19 US disclosed
US-7872009-B2 Beta-Secretase modulators and methods of use AMGEN INC. (US) 2011-01-18 US disclosed
US-7786135-B2 Substituted pyrroline kinase inhibitors JANSSEN PHARMACEUTICA, N.V. (BE) 2010-08-31 US disclosed
EP-0856002-B1 PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS UPJOHN CO (US) 2001-10-24 EP disclosed
US-6166056-A Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings PHARMACIA (US) 2000-12-26 US disclosed
US-6051716-A ANTIMICROBIAL AGENTS PHARMACIA & UPJOHN, INC. (US) 2000-04-18 US disclosed
US-6043266-A MICROBIOCIDES TREATING GRAM-POSITIVE BACTERIA INFECTIONS AND PERSONS WITH AIDS PHARMACIA & UPJOHN COMPANY (US) 2000-03-28 US disclosed
US-5968962-A ANTIMICROBIAL AGENTS; EFFECTIVE AGAINST GRAMPOSITIVE BACTERIA PHARMACIA & UPJOHN COMPANY (US) 1999-10-19 US disclosed
EP-0856002-A1 PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS PHARMACIA &amp; UPJOHN COMPANY (US) 1998-08-05 EP disclosed
US-5635501-A Alphalosporins and 1-carba-1-dethia cephalosporins PFIZER INC. (US) 1997-06-03 US disclosed
WO-1997009328-A1 PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS PHARMACIA & UPJOHN COMPANY (US) 1997-03-13 WO disclosed
EP-0647230-A1 CEPHALOSPORINS AND 1-CARBA-1-DETHIA CEPHALOSPORINS PFIZER INC. (US) 1995-04-12 EP disclosed
WO-1994000457-A1 ALPHALOSPORINS AND 1-CARBA-1-DETHIA CEPHALOSPORINS SMITHKLINE BEECHAM P.L.C. (GB) 1994-01-06 WO disclosed