Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113186 | 1.00 | MAPT (0.61) | MAPTGAAKDM4EHPGDTAS2R38 | |
| SCHEMBL12440049 | 1.00 | MAPT (0.61) | MAPTGAAKDM4EHPGDTAS2R38 | |
| SCHEMBL19005463 | 0.83 | RAB9A (0.46) | MAPTGAAKDM4EHPGDHSD17B10 | |
| SCHEMBL24378992 | 0.82 | MAPT (0.63) | MAPTGAAKDM4EHPGDTAS2R38 | |
| SCHEMBL28067506 | 0.81 | MAPT (0.57) | MAPTGAAKDM4EHPGDTAS2R38 | |
| SCHEMBL19987385 | 0.81 | MAPT (0.52) | MAPTGAAKDM4EHPGDTAS2R38 | |
| SCHEMBL21511125 | 0.79 | SMN1; SMN2 (0.59) | MAPTKDM4EHPGDHSD17B10NAPRT | |
| SCHEMBL24736926 | 0.79 | MAPT (0.56) | MAPTGAAKDM4EHPGDHSD17B10 | |
| SCHEMBL18890669 | 0.78 | TDP1 (0.58) | MAPTKDM4EHPGDNPC1RAB9A | |
| SCHEMBL3069783 | 0.78 | MAPT (0.75) | MAPTGAAKDM4EHPGDTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058205-A | The method for preparing pyridine and quinoline | HOECHST CELANESE CORP (US) | 1992-01-29 | — | — | CN | claimed |
| CN-105272904-B | N- phenylamide compound and its application | 中国科学院广州生物医药与健康研究院 | 2019-04-09 | — | — | CN | disclosed |
| WO-2017029394-A1 | ELASTOMERIC POLYMER | TRINSEO EUROPE GMBH (CH) | 2017-02-23 | — | — | WO | disclosed |
| CN-105272904-A | N-phenylamide compound and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2016-01-27 | — | — | CN | disclosed |
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |