Sugi Predict

Sugi Predict / Compounds / SCHEMBL9254019

SCHEMBL9254019

SCHEMBL9254019

COC1(c2cccc(S(=O)(=O)c3ccc(N(C)C(=O)N(C)C)cc3)c2)CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 10/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9255281 0.86 ALOX5 (0.41) ALOX5
SCHEMBL9440190 0.81 ALOX5 (0.45) ALOX5
SCHEMBL9254515 0.80 ALOX5 (0.38) ALOX5
SCHEMBL9385324 0.80 FSCN1 (0.39) ALOX5
SCHEMBL9254837 0.80 ALOX5 (0.52) ALOX5
SCHEMBL9385108 0.78 ALOX5 (0.60) ALOX5
SCHEMBL9074400 0.78 ALOX5 (0.41) ALOX5
SCHEMBL9074404 0.78 ALOX5 (0.41) ALOX5
SCHEMBL9074407 0.78 ALOX5 (0.41) ALOX5
SCHEMBL9253375 0.78 ALOX5 (0.63) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5432194-A Antiallergens, antinflammatory agents ABBOTT LABORATORIES (US) 1995-07-11 — — US claimed
US-5432194-A Antiallergens, antinflammatory agents ABBOTT LABORATORIES (US) 1995-07-11 — — US disclosed
WO-1994026264-A1 (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE ABBOTT LABORATORIES (US) 1994-11-24 — — WO disclosed
US-5346914-A Antiallergens, antiinflammatory agents ABBOTT LABORATORIES (US) 1994-09-13 — — US disclosed