Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255108 | 0.89 | POLB (0.37) | POLBAPEX1TDP1TSHRPTPN1 | |
| SCHEMBL9259592 | 0.77 | MEN1 (0.41) | CHRM2MEN1CYP2D6KMT2ATSHR | |
| SCHEMBL9259143 | 0.76 | CA9 (0.37) | POLBCYP2D6TSHRPTPN1ALDH1A1 | |
| SCHEMBL9257711 | 0.76 | CHRM2 (0.42) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL7154470 | 0.75 | TSHR (0.44) | POLBCHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL7151917 | 0.75 | TSHR (0.44) | POLBCHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL8329413 | 0.75 | TSHR (0.44) | POLBCHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL1266094 | 0.75 | TSHR (0.44) | POLBCHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL21510391 | 0.75 | TSHR (0.44) | POLBCHRM2MEN1CYP2D6KMT2A | |
| SCHEMBL7152812 | 0.75 | TSHR (0.44) | POLBCHRM2MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422365-A | Hydroxy, ether, and/or acyloxy substituted, saturated or partially unsaturated naphthalenes; for controlling insulin secretion | ADIR ET COMPAGNIE (FR) | 1995-06-06 | — | — | US | disclosed |