Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ATF4 | P18848 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254407 | 1.00 | CHRNA3 (0.40) | CHRNA3HPGDATF4KMT2AHTT | |
| SCHEMBL9254403 | 1.00 | CHRNA3 (0.40) | CHRNA3HPGDATF4KMT2AHTT | |
| SCHEMBL9249616 | 0.94 | CHRNA3 (0.39) | CHRNA3HPGDATF4KMT2AHTT | |
| SCHEMBL9249612 | 0.94 | CHRNA3 (0.39) | CHRNA3HPGDATF4KMT2AHTT | |
| SCHEMBL9249607 | 0.94 | CHRNA3 (0.39) | CHRNA3HPGDATF4KMT2AHTT | |
| SCHEMBL9252988 | 0.92 | HPGD (0.40) | HPGDKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9252996 | 0.92 | HPGD (0.40) | HPGDKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9252992 | 0.92 | HPGD (0.40) | HPGDKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9876154 | 0.90 | KMT2A (0.38) | HPGDKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL9876157 | 0.90 | KMT2A (0.38) | HPGDKMT2AHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5013477-A | Alkenylbicyclohexane liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |