Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 16/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 16/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | CDC42 | P60953 | 1/20 | 0.57 |
| ▸ | RAC1 | P63000 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737441 | 1.00 | AKR1C3 (0.57) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL13038659 | 0.88 | AKR1B1 (0.59) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL259779 | 0.88 | AKR1B1 (0.59) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11467554 | 0.85 | AKR1C3 (0.64) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL27513099 | 0.84 | AKR1C3 (0.50) | AKR1C3AKR1C2PTGS2PTGS1SLC22A6 | |
| SCHEMBL25627487 | 0.81 | HDAC4 (0.54) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11468163 | 0.80 | AKR1B1 (0.60) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11467673 | 0.79 | AKR1C3 (0.64) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11742705 | 0.78 | AKR1C3 (0.73) | AKR1C3AKR1C2PTGS2PTGS1CDC42 | |
| SCHEMBL11742912 | 0.78 | ALDH1A1 (0.43) | CYP1A2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644940-A1 | PROCESS FOR ENZYMATIC PREPARATION OF -i(S)-6-METHOXY-A-METHYL-2-MAPHTHALENEACETIC ACID | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1995-03-29 | — | — | EP | disclosed |