Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222736 | 0.76 | KMT2A (0.47) | KMT2ANPSR1ALDH1A1GFER | |
| SCHEMBL2366051 | 0.74 | TDP1 (0.41) | KMT2AALDH1A1CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL25319890 | 0.73 | — | — | |
| SCHEMBL7597819 | 0.72 | IDO1 (0.36) | KMT2ANPSR1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9686971 | 0.69 | TSHR (0.47) | KMT2ANPSR1ALDH1A1GFERCYP3A4 | |
| SCHEMBL11095504 | 0.69 | KMT2A (0.44) | KMT2ANPSR1ALDH1A1GFERL3MBTL1 | |
| SCHEMBL8648187 | 0.68 | KMT2A (0.60) | KMT2ANPSR1ALDH1A1GFERCYP3A4 | |
| SCHEMBL377259 | 0.67 | KMT2A (1.00) | KMT2ANPSR1ALDH1A1GFERMAPT | |
| SCHEMBL30162631 | 0.67 | KMT2A (1.00) | KMT2ANPSR1ALDH1A1GFERMAPT | |
| SCHEMBL11779597 | 0.67 | AHR (0.40) | KMT2ACYP3A4ALOX15TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475112-A | Reducing a substituted trichloromethylpyridine derivative in presence of a proton donor and solvent | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0512436-A1 | Method for producing substituted pyridine derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4521603-A | Continuous process for the production of polybromopyridine compounds | OLIN CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-3974166-A | FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |
| US-3956340-A | Process for the production of polyhalogenated nicotinic acids | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3956340-A | Process for the production of polyhalogenated nicotinic acids | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |