SCHEMBL11095504

SCHEMBL11095504

ClCc1cccc2cc(Cl)c(Cl)nc12

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.37
CCR1 P32246 1/20 0.37
CCR8 P51685 1/20 0.37
DRD4 P21917 1/20 0.36
DRD3 P35462 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TERT O14746 4/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GFER P55789 1/20 0.32
PNMT P11086 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27913880 0.82 TERT (0.46) KMT2AL3MBTL1CCR1CCR8DRD4
SCHEMBL28827733 0.77 KMT2A (0.53) KMT2AL3MBTL1DRD4DRD3ALDH1A1
SCHEMBL27792869 0.73 SLC40A1 (0.41) KMT2ACCR1CCR8NPSR1
SCHEMBL1119653 0.73 NQO2 (0.50) KMT2AALDH1A1MEN1
SCHEMBL29036056 0.73 NR4A2 (0.40) KMT2AL3MBTL1CCR1CCR8ALDH1A1
SCHEMBL24971012 0.73 DRD4 (0.51) KMT2AL3MBTL1DRD4DRD3ALDH1A1
SCHEMBL31142923 0.73 DRD4 (0.51) KMT2AL3MBTL1DRD4DRD3ALDH1A1
SCHEMBL27510182 0.72 NQO2 (0.49) KMT2AALDH1A1MEN1
SCHEMBL788752 0.71 DRD4 (0.61) KMT2AL3MBTL1DRD4DRD3ALDH1A1
SCHEMBL27991437 0.70 L3MBTL1 (0.37) L3MBTL1CCR1CCR8DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0060429-B1 DICHLOROQUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1984-01-25 EP disclosed
EP-0060429-A1 Dichloroquinoline derivatives, their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-09-22 EP disclosed