Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293854 | 1.00 | NPC1 (0.48) | NPC1RAB9AL3MBTL1BCHECPT2 | |
| SCHEMBL7293860 | 1.00 | NPC1 (0.48) | NPC1RAB9AL3MBTL1BCHECPT2 | |
| SCHEMBL7282436 | 0.92 | NPC1 (0.50) | NPC1RAB9ABCHECPT2CPT1A | |
| SCHEMBL7282447 | 0.92 | NPC1 (0.50) | NPC1RAB9ABCHECPT2CPT1A | |
| SCHEMBL9183602 | 0.89 | NPC1 (0.52) | NPC1RAB9ABCHECPT2CPT1A | |
| SCHEMBL7283382 | 0.89 | NPC1 (0.52) | NPC1RAB9ABCHECPT2CPT1A | |
| SCHEMBL7283375 | 0.89 | NPC1 (0.52) | NPC1RAB9ABCHECPT2CPT1A | |
| SCHEMBL7284724 | 0.87 | L3MBTL1 (0.49) | NPC1RAB9AL3MBTL1BCHECPT2 | |
| SCHEMBL7284726 | 0.87 | L3MBTL1 (0.49) | NPC1RAB9AL3MBTL1BCHECPT2 | |
| SCHEMBL7282414 | 0.85 | NPC1 (0.46) | NPC1RAB9AL3MBTL1BCHECPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411974-A | Thiazoline derivatives, treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |