Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217024 | 0.81 | PPM1B (0.35) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL20230431 | 0.81 | PPM1B (0.35) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL20217055 | 0.81 | PPM1B (0.35) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL20230433 | 0.81 | PPM1B (0.35) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL20217023 | 0.76 | MGAM (0.35) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL30747427 | 0.76 | MEN1 (0.40) | KMT2AALDH1A1LMNAPPM1BPTPN1 | |
| SCHEMBL9005307 | 0.74 | MIF (0.36) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL6270051 | 0.74 | MIF (0.36) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL2224202 | 0.73 | SIGMAR1 (0.37) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL2224200 | 0.73 | SIGMAR1 (0.37) | GAAMGAMSIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642353-A1 | TREATMENT OF VASCULAR LEAKAGE SYNDROME AND COLLAGENASE INDUCED DISEASE BY ADMINISTRATION OF MATRIX METALLOPROTEINASE INHIBITORS | ONCOLOGIX, INC. (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993023075-A1 | TREATMENT OF VASCULAR LEAKAGE SYNDROME AND COLLAGENASE INDUCED DISEASE BY ADMINISTRATION OF MATRIX METALLOPROTEINASE INHIBITORS | ONCOLOGIX, INC. (US) | 1993-11-25 | — | — | WO | disclosed |