SCHEMBL9254539

SCHEMBL9254539

COC1(c2cc(F)cc(Sc3ccc(N(C)C(=O)N(C)C)cc3)c2)CCOCC1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 19/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9249393 0.87 ALOX5 (0.46) ALOX5
SCHEMBL9254958 0.86 ALOX5 (0.54) ALOX5
SCHEMBL9259112 0.86 ALOX5 (0.43) ALOX5
SCHEMBL9254837 0.85 ALOX5 (0.52) ALOX5
SCHEMBL9253996 0.84 ALOX5 (0.51) ALOX5
Hydrochloric Acid SCHEMBL9258186 0.83 ALOX5 (0.51) ALOX5
SCHEMBL9049483 0.83 ALOX5 (0.51) ALOX5
SCHEMBL9048209 0.82 ALOX5 (0.44) ALOX5
SCHEMBL9049773 0.82 ALOX5 (0.46) ALOX5
SCHEMBL9254294 0.81 ALOX5 (0.41) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5432194-A Antiallergens, antinflammatory agents ABBOTT LABORATORIES (US) 1995-07-11 US claimed
US-5432194-A Antiallergens, antinflammatory agents ABBOTT LABORATORIES (US) 1995-07-11 US disclosed