Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539159 | 0.83 | TTPA (0.49) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8540281 | 0.78 | TTPA (0.46) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8543302 | 0.77 | TTPA (0.45) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8542945 | 0.75 | TTPA (0.44) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8544229 | 0.75 | TTPA (0.44) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8542195 | 0.75 | TTPA (0.42) | TTPAALOX5MEN1KMT2ACYP3A4 | |
| SCHEMBL8537141 | 0.75 | TTPA (0.43) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8544164 | 0.75 | TTPA (0.43) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8538768 | 0.74 | TTPA (0.56) | TTPAALOX5MEN1KMT2APDE4A | |
| SCHEMBL8543959 | 0.74 | CYP2C9 (0.43) | TTPAALOX5MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |