Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204613 | 0.95 | CYP4F2 (0.46) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL1519333 | 0.84 | CYP4F2 (0.50) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL9412105 | 0.84 | SMN1; SMN2 (0.43) | TSHRL3MBTL1GAALMNAPOLB | |
| SCHEMBL9255523 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL1519281 | 0.82 | POLB (0.58) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL9255724 | 0.82 | CYP4F2 (0.54) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL1519467 | 0.82 | CYP4F2 (0.48) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL7483813 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL7483826 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11TSHRL3MBTL1GAA | |
| SCHEMBL7490164 | 0.81 | CYP4F2 (0.51) | CYP4F2CYP4A11TSHRL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |