Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203233 | 0.95 | CYP4F2 (0.47) | CYP4F2CYP4A11KDM4EATMPOLB | |
| SCHEMBL23420316 | 0.90 | ALDH1A1 (0.48) | CYP4F2CYP4A11KDM4EATMPOLB | |
| SCHEMBL1519333 | 0.85 | CYP4F2 (0.50) | CYP4F2CYP4A11KDM4EATMPOLB | |
| SCHEMBL23420330 | 0.83 | USP2 (0.53) | CYP4F2CYP4A11KDM4EATMPOLB | |
| SCHEMBL9254561 | 0.83 | CYP4F2 (0.46) | CYP4F2CYP4A11ATMPOLBALDH1A1 | |
| SCHEMBL1519281 | 0.83 | POLB (0.58) | CYP4F2CYP4A11KDM4EPOLBALDH1A1 | |
| SCHEMBL1519467 | 0.83 | CYP4F2 (0.48) | CYP4F2CYP4A11KDM4EATMPOLB | |
| SCHEMBL9255724 | 0.83 | CYP4F2 (0.54) | CYP4F2CYP4A11KDM4EATMPOLB | |
| SCHEMBL7483813 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11POLBALDH1A1RECQL | |
| SCHEMBL7483826 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11POLBALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |