Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250218 | 0.87 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9250589 | 0.85 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9246947 | 0.82 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9255974 | 0.80 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL8953659 | 0.76 | SIRT2 (0.38) | TSHR | |
| SCHEMBL9250493 | 0.73 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9259112 | 0.72 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9247548 | 0.72 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL9251045 | 0.72 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL8783640 | 0.72 | ALOX5 (0.59) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |