SCHEMBL9254735

SCHEMBL9254735

C=Cc1ccccc1C=C.O=C1C=C(C=Cc2ccccc2)C(=O)O1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.38
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
TRPA1 O75762 2/20 0.36
NFE2L2 Q16236 2/20 0.36
TSHR P16473 1/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ELANE P08246 1/20 0.35
MAOA P21397 1/20 0.34
CMA1 P23946 1/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
DPYD Q12882 1/20 0.33
IP6K1 Q92551 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28079565 0.90 ALDH1A1 (0.47) MAOBALDH1A1SMN1; SMN2LMNATRPA1
Butadiene SCHEMBL28470024 0.89 ALDH1A1 (0.36) MAOBALDH1A1SMN1; SMN2LMNATRPA1
SCHEMBL218671 0.88 ALDH1A1 (0.40) MAOBALDH1A1SMN1; SMN2LMNATRPA1
Styrene SCHEMBL27534959 0.88 ALDH1A1 (0.44) MAOBALDH1A1SMN1; SMN2LMNATRPA1
Vinyl Chloride SCHEMBL679798 0.87 ALDH1A1 (0.36) MAOBALDH1A1SMN1; SMN2LMNATRPA1
Ammonia Solution, Strong SCHEMBL11795784 0.87 ALDH1A1 (0.39) MAOBALDH1A1SMN1; SMN2LMNATRPA1
SCHEMBL3902558 0.87 ALDH1A1 (0.39) MAOBALDH1A1SMN1; SMN2LMNATRPA1
SCHEMBL29506835 0.87 ALDH1A1 (0.39) MAOBALDH1A1SMN1; SMN2LMNATRPA1
Hydrochloric Acid SCHEMBL4231752 0.87 ALDH1A1 (0.39) MAOBALDH1A1SMN1; SMN2LMNATRPA1
Lithium SCHEMBL30891430 0.87 ALDH1A1 (0.39) MAOBALDH1A1SMN1; SMN2LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5461096-A Nondripping GENERAL ELECTRIC COMPANY (US) 1995-10-24 US disclosed
EP-0550204-A2 Polyphenylene ether resin compositions GENERAL ELECTRIC COMPANY (US) 1993-07-07 EP disclosed
EP-0078834-B1 NOVEL POLYPHENYLENE OXIDE BLENDS GENERAL ELECTRIC COMPANY (US) 1987-01-28 EP disclosed
US-4536542-A REDUCTION OF GLOSS BY BLENDING WITH ETHYLENE, CARBON MONOXIDE, ANDTHIRD MONOMER TERPOLYMER GENERAL ELECTRIC COMPANY (US) 1985-08-20 US disclosed
EP-0142802-A2 Method for altering the surface of thermoplastic polymers GENERAL ELECTRIC COMPANY (US) 1985-05-29 EP disclosed
US-4446278-A POLYCARBONATE-ETHER BLOCK POLYMER, VINYLAROMATIC POLYMER GENERAL ELECTRIC COMPANY (US) 1984-05-01 US disclosed
EP-0078834-A4 NOVEL POLYPHENYLENE OXIDE BLENDS. GEN ELECTRIC (US) 1983-09-02 EP disclosed
EP-0078834-A1 NOVEL POLYPHENYLENE OXIDE BLENDS. GEN ELECTRIC (US) 1983-05-18 EP disclosed
WO-1982004056-A1 NOVEL POLYPHENYLENE OXIDE BLENDS GEN ELECTRIC (US) 1982-11-25 WO disclosed
US-4355126-A VINYL AROMATIC RESIN, POLYTETRAFLUOROETHYLENE GENERAL ELECTRIC COMPANY (US) 1982-10-19 US disclosed
US-4247662-A Novel halobisphenolethylene polycarbonate-vinyl aromatic resin blends GENERAL ELECTRIC COMPANY (US) 1981-01-27 US disclosed
US-4107232-A HALOGENATED COMPOUND, POLYTETRAFLUOROETHYLENE GENERAL ELECTRIC (US) 1978-08-15 US disclosed