Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.75 |
| ▸ | PIM1 | P11309 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | NAT1 | P18440 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254899 | 1.00 | GSK3B (0.75) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL8177338 | 0.86 | GSK3B (0.58) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL8177340 | 0.86 | GSK3B (0.58) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL8167446 | 0.84 | GSK3B (0.54) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL17447088 | 0.75 | PIM1 (0.52) | PIM1MEN1KMT2ANAT1CA2 | |
| SCHEMBL12892074 | 0.75 | PIM1 (0.68) | PIM1MEN1KMT2ARAB9ANAT1 | |
| SCHEMBL1250382 | 0.74 | PIM1 (1.00) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL1250384 | 0.74 | PIM1 (1.00) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL24991995 | 0.74 | CRHBP (0.46) | GSK3BPIM1MEN1KMT2ARAB9A | |
| SCHEMBL24992659 | 0.73 | CRHBP (0.51) | PIM1MEN1KMT2ARAB9ANAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | claimed |
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5208250-A | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |