Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 9/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255590 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9253641 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9257387 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9255881 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9250686 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9251339 | 0.81 | HPGD (0.49) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9258560 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2BF10F2PRSS1 | |
| SCHEMBL9253069 | 0.80 | MAP4K4 (0.50) | ITGB3ITGA2BF10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL9254302 | 0.80 | HPGD (0.48) | ITGB3ITGA2BF10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL9254391 | 0.79 | ST14 (0.54) | ITGB3ITGA2BF10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |