Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256719 | 0.86 | THRB (0.45) | MAPTSMN1; SMN2KMT2ATHRBATM | |
| SCHEMBL9257554 | 0.84 | MAPT (0.43) | MAPTSMN1; SMN2KMT2ATHRBTP53 | |
| SCHEMBL9253679 | 0.84 | RARB (0.40) | MAPTSMN1; SMN2KMT2ARARBALDH1A1 | |
| SCHEMBL10000259 | 0.83 | RARB (0.62) | MAPTSMN1; SMN2KMT2ATHRBTP53 | |
| SCHEMBL9252022 | 0.83 | RARB (0.40) | MAPTSMN1; SMN2KMT2ATP53RARB | |
| SCHEMBL9878447 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ATHRBRARB | |
| SCHEMBL9878498 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ATHRBRARB | |
| SCHEMBL9878709 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ATHRBRARB | |
| SCHEMBL9878771 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ATHRBRARB | |
| SCHEMBL9878535 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ATHRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5013477-A | Alkenylbicyclohexane liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |