Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 9/20 | 0.50 |
| ▸ | TTPA | P49638 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314914 | 0.91 | PSEN1 (0.52) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9252690 | 0.87 | TTPA (0.46) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9265495 | 0.85 | PTGS1 (0.49) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9313634 | 0.80 | MEN1 (0.50) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9314093 | 0.79 | TTPA (0.47) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9257195 | 0.79 | PSEN1 (0.47) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9314035 | 0.78 | TTPA (0.47) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9268591 | 0.78 | TTPA (0.43) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9313955 | 0.78 | PTGS1 (0.55) | PSEN1TTPAALOX5CYP1A2CYP3A4 | |
| SCHEMBL9257210 | 0.75 | PTGS1 (0.52) | PSEN1TTPAALOX5CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |