SCHEMBL9255336

SCHEMBL9255336

CCN1CCC(N)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318757 1.00
SCHEMBL16190279 1.00
SCHEMBL9611931 0.88 CYP3A4 (0.41)
SCHEMBL14275832 0.88 CYP3A4 (0.41)
SCHEMBL1527371 0.86 CYP3A4 (0.39)
SCHEMBL1527372 0.86 CYP3A4 (0.39)
Hydrochloric Acid SCHEMBL15123892 0.86 CYP3A4 (0.39)
Hydrochloric Acid SCHEMBL320458 0.86 CYP3A4 (0.39)
SCHEMBL4704959 0.86 CYP3A4 (0.39)
SCHEMBL7804695 0.84 L3MBTL1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5384406-A Hydrolysis resistant; agriculture chemical anions ISP INVESTMENTS INC. (US) 1995-01-24 US claimed
WO-1992021656-A1 WATER-SOLUBLE BIOLOGICALLY ACTIVE AMMONIUM SALTS ISP INVESTMENTS INC. (US) 1992-12-10 WO claimed
US-11873304-B2 Fused pyrimidine derivatives as A2A/A2B inhibitors INCYTE CORPORATION (US) 2024-01-16 US disclosed
WO-2023230540-A2 INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed
US-11168089-B2 Fused pyrimidine derivatives as A2A / A2B inhibitors INCYTE CORPORATION (US) 2021-11-09 US disclosed
EP-3810610-A1 FUSED PYRIMIDINE DERIVATIVES AS A2A / A2B INHIBITORS Incyte Corporation (US) 2021-04-28 EP disclosed
US-20180110766-A1 SELECTIVE NR2B ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2018-04-26 US disclosed
US-20180104265-A1 (R)-3-((3S,4S)-3-FLUORO-4-(4-HYDROXYPHENYL)PIPERIDIN-1-YL)-1-(4-METHYLBENZYL)PYRROLIDIN-2-ONE AND ITS PRODRUGS FOR THE TREATMENT OF PSYCHIATRIC DISORDERS BRISTOL MYERS SQUIBB CO (US) 2018-04-19 US disclosed
US-20180000807-A1 SELECTIVE NR2B ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2018-01-04 US disclosed
US-20170340653-A1 (R)-3-((3S,4S)-3-FLUORO-4-(4-HYDROXYPHENYL)PIPERIDIN-1-YL)-1-(4-METHYLBENZYL)PYRROLIDIN-2-ONE AND ITS PRODRUGS FOR THE TREATMENT OF PSYCHIATRIC DISORDERS BRISTOL MYERS SQUIBB CO (US) 2017-11-30 US disclosed
US-20170258777-A1 Selective NR2B Antagonists BRISTOL MYERS SQUIBB CO (US) 2017-09-14 US disclosed
US-7332509-B2 Heterocyclic amides, a process for their preparation, compositions comprising them and their use MERIAL LIMITED (US) 2008-02-19 US disclosed
US-7332509-B2 Heterocyclic amides, a process for their preparation, compositions comprising them and their use MERIAL LIMITED (US) 2008-02-19 US disclosed
EP-1434485-B1 NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES FOR USE AS PESTICIDES MERIAL LTD (US) 2007-05-16 EP disclosed
US-5384406-A Hydrolysis resistant; agriculture chemical anions ISP INVESTMENTS INC. (US) 1995-01-24 US disclosed
US-5334331-A A stripping solution mixture comprising gamma-butyrolactone, a cyclomethicone; nontoxic, biodegradable, water solubility, corrosion resistance ISP INVESTMENTS INC. (US) 1994-08-02 US disclosed
WO-1994015727-A1 METHOD OF ACTIVATING N-METHYL-2-PYRROLIDONE (NMP) VARNISH AND PAINT REMOVER SOLVENTS FOR REMOVAL OF ORGANIC COATINGS ISP INVESTMENTS INC. (US) 1994-07-21 WO disclosed
WO-1993018865-A1 AQUEOUS STRIPPING COMPOSITION CONTAINING A PEROXIDE AND BUTYROLACTONE, ETHYLENE CARBONATE OR A WATER SOLUBLE ESTER ISP INVESTMENTS INC. (US) 1993-09-30 WO disclosed
US-5221791-A Hydrolysis resistant ISP INVESTMENTS INC. (US) 1993-06-22 US disclosed
US-5215675-A Aqueous stripping composition containing peroxide and water soluble ester ISP INVESTMENTS INC. (US) 1993-06-01 US disclosed