Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073887 | 0.78 | TYR (0.64) | TYRMAPK1KDM4EGRIN2DGRIN3B | |
| SCHEMBL23918549 | 0.78 | TYR (0.64) | TYRMAPK1KDM4EGRIN2DGRIN3B | |
| SCHEMBL30075786 | 0.78 | TYR (0.64) | TYRMAPK1KDM4EGRIN2DGRIN3B | |
| Hydrogen Peroxide SCHEMBL182135 | 0.76 | TYR (0.55) | TYRMAPK1KDM4EPTGS1SMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL20915049 | 0.76 | TYR (0.55) | TYRMAPK1KDM4EPTGS1SMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL461155 | 0.76 | TYR (0.55) | TYRMAPK1KDM4EPTGS1SMN1; SMN2 | |
| SCHEMBL104124 | 0.76 | TYR (0.58) | TYRMAPK1KDM4EPTGS1NPC1 | |
| SCHEMBL139407 | 0.76 | TYR (0.61) | TYRMAPK1KDM4EGRIN2DGRIN3B | |
| SCHEMBL9637970 | 0.75 | TYR (0.54) | TYRMAPK1KDM4EGRIN2DGRIN3B | |
| SCHEMBL12027409 | 0.75 | TYR (0.54) | TYRMAPK1KDM4EGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455262-A | Treating arthritis, tumor metastasis, periodontal disease, corneal ulceration, bone resorption diseases, glomerular diseases | FLORIDA STATE UNIVERSITY (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0071126-B1 | PROCESS FOR THE MANUFACTURE OF ALDEHYDES | BAYER AG (DE) | 1984-09-12 | — | — | EP | disclosed |
| EP-0071126-A1 | Process for the manufacture of aldehydes | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |