Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632525 | 0.81 | PTGDR2 (0.59) | PTGDR2HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL10632447 | 0.79 | PTGDR2 (0.62) | PTGDR2HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL12129219 | 0.77 | HTR1D (0.61) | PTGDR2HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL4222005 | 0.77 | PTGDR2 (0.61) | PTGDR2SLC6A4SLC6A2SLC6A3TSHR | |
| SCHEMBL2586792 | 0.76 | PTGDR2 (0.50) | PTGDR2HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL195657 | 0.76 | PTGDR2 (0.62) | PTGDR2HTR1DHTR1BHTR1ASLC6A4 | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.75 | HPGD (0.60) | HTR1ASLC6A4CYP1A2CYP2D6ADRA1A | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.75 | HPGD (0.60) | HTR1ASLC6A4CYP1A2CYP2D6ADRA1A | |
| SCHEMBL20052525 | 0.75 | HTR2C (0.41) | PTGDR2HTR1ASLC6A4ADRA2ADRD3 | |
| SCHEMBL11127696 | 0.75 | PTGDR2 (0.60) | PTGDR2HTR1DHTR1BHTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380654-A | Process for the preparation of epoxides of means of microorganisms | JAPAN ENERGY CORPORATION (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5376539-A | Aerobic incubation of allyl phenyl ether with arthrobacter, brevibacterium, corynebacterium, pseudomonas or rhodococcus yields glycidyl phenyl ether | NIPPON MINING CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0301402-B1 | LEUKOTRIENE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF ILLNESSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-21 | — | — | EP | disclosed |
| EP-0166527-B1 | A PROCESS FOR THE PREPARATION OF EPOXIDES BY MEANS OF MICROORGANISMS | NIPPON MINING COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0411787-A2 | Microbiological production of 2,3-epoxypropyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-06 | — | — | EP | disclosed |
| US-4855323-A | Leukotriene antagonists, a process for the preparation thereof, and the use thereof for the treatment of diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0301402-A1 | Leukotriene antagonists, process for their preparation and their use in the treatment of illnesses | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-01 | — | — | EP | disclosed |
| EP-0166527-A2 | A process for the preparation of epoxides by means of microorganisms | NIPPON MINING COMPANY LIMITED (JP) | 1986-01-02 | — | — | EP | disclosed |