Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255780 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL8123104 | 0.78 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL8123102 | 0.78 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL4543896 | 0.76 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1 | |
| SCHEMBL919522 | 0.70 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL30530488 | 0.70 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL919524 | 0.70 | CYSLTR1 (0.57) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL5708661 | 0.68 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL5708663 | 0.68 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1MEN1KMT2ANPC1 | |
| SCHEMBL18002621 | 0.67 | PTGS1 (0.50) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472964-A | Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1995-12-05 | — | — | US | disclosed |