Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255995 | 1.00 | MAPT (0.44) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL14518050 | 0.85 | MAPT (0.55) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL9358086 | 0.85 | MAPT (0.55) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL13996078 | 0.75 | CYP2A6 (0.57) | MAPTKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL9258918 | 0.75 | GALR3 (0.41) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL9258908 | 0.75 | GALR3 (0.41) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL28961841 | 0.72 | GOT1 (0.53) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL28961875 | 0.72 | GOT1 (0.53) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL28961838 | 0.72 | GOT1 (0.53) | MAPTKMT2AMEN1HTTGALR3 | |
| SCHEMBL12792096 | 0.71 | MAPT (0.43) | MAPTKMT2AMEN1HTTGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |