Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 3/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | RARG | P13631 | 3/20 | 0.47 |
| ▸ | NQO2 | P16083 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256093 | 1.00 | PTGS2 (0.50) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL9251415 | 0.76 | PTGS1 (0.56) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL9251408 | 0.76 | PTGS1 (0.56) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL9255534 | 0.75 | PTGS2 (0.54) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL9260388 | 0.75 | PTGS2 (0.50) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL9255530 | 0.75 | PTGS2 (0.54) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL11834984 | 0.75 | PTGS1 (0.50) | PTGS2PTGS1ESR1ESR2NQO2 | |
| SCHEMBL9260391 | 0.75 | PTGS2 (0.50) | PTGS2PTGS1ESR1ESR2RARA | |
| SCHEMBL3692880 | 0.75 | TSHR (0.48) | ESR1ESR2TSHRHSD17B10BACE1 | |
| SCHEMBL3751900 | 0.73 | TSHR (0.46) | ESR1ESR2TSHRHSD17B10BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382693-A | Curing agents for epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| WO-1994026690-A1 | BIS(AMINOPHENOXY)-ALPHA-SUBSTITUTED STILBENES, CURABLE MIXTURES WITH EPOXY RESINS AND CURED PRODUCTS | THE DOW CHEMICAL COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5300594-A | Bis(aminophenoxy)-alpha-substituted stilbenes, curable mixtures with epoxy resins and cured products | THE DOW CHEMICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |