SCHEMBL9256411

SCHEMBL9256411

COC1(c2cccc(OCc3ccc(CN4CCNC4=O)cc3)c2)CCOCC1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9251255 0.87 ALOX5 (0.63) ALOX5
SCHEMBL9228533 0.76 ALOX5 (1.00) ALOX5
SCHEMBL9030881 0.76 ALOX5 (0.62) ALOX5
SCHEMBL9203742 0.75 ALOX5 (0.64) ALOX5
SCHEMBL8696022 0.75 ALOX5 (0.77) ALOX5
SCHEMBL8783169 0.75 ALOX5 (0.61) ALOX5
SCHEMBL8698212 0.75 ALOX5 (0.61) ALOX5
SCHEMBL9253375 0.74 ALOX5 (0.63) ALOX5
SCHEMBL9219105 0.74 ALOX5 (1.00) ALOX5
SCHEMBL9246947 0.74 ALOX5 (0.62) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5432194-A Antiallergens, antinflammatory agents ABBOTT LABORATORIES (US) 1995-07-11 US disclosed
US-5346914-A Antiallergens, antiinflammatory agents ABBOTT LABORATORIES (US) 1994-09-13 US disclosed