Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208524 | 0.74 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL17667571 | 0.74 | MEN1 (0.58) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL17667569 | 0.74 | MEN1 (0.58) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL7863751 | 0.74 | CA9 (0.45) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL1779718 | 0.71 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CTDP2 | |
| SCHEMBL16294213 | 0.70 | PARP1 (0.44) | PNMTADRA2APARP1ADRA2BADRA2C | |
| SCHEMBL4976676 | 0.69 | PARP1 (0.52) | PARP1 | |
| SCHEMBL383577 | 0.69 | PNMT (0.74) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL7382123 | 0.69 | PARP1 (0.52) | PARP1 | |
| SCHEMBL11142660 | 0.69 | PARP1 (0.52) | PARP1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501099-A | The adjusting control agent of ATP combination cassette transporters | 沃泰克斯药物股份有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-104788328-B | The adjusting control agent of ATP combination cassette transporters | 沃泰克斯药物股份有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-103641765-B | ATP-combines the adjusting control agent of cassette transporters | 沃泰克斯药物股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-101935301-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2011-01-05 | — | — | CN | disclosed |
| CN-101891680-A | The adjusting control agent of ATP- combination cassette transporters | VERTEX PHARMA | 2010-11-24 | — | — | CN | disclosed |
| US-5464871-A | Aromatic amides | OCTAMER, INC. (US) | 1995-11-07 | — | — | US | disclosed |