Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258548 | 0.89 | ESR2 (0.40) | EGLN1ESR2FFAR1AKR1B1GBA1 | |
| SCHEMBL9255943 | 0.85 | EGLN1 (0.46) | EGLN1ESR2FFAR1AKR1B1GBA1 | |
| SCHEMBL7312739 | 0.84 | PPARG (0.45) | ESR2GSK3AGSK3BAXLFLT3 | |
| SCHEMBL9257925 | 0.83 | PPARG (0.41) | ESR2GSK3AGSK3BPPARG | |
| SCHEMBL902910 | 0.81 | NPC1 (0.40) | EGLN1ESR2GHSRCCNE1CDK2 | |
| SCHEMBL9256116 | 0.74 | EGLN1 (0.46) | EGLN1ESR2FFAR1AKR1B1GBA1 | |
| SCHEMBL6960030 | 0.74 | ESR2 (0.59) | EGLN1ESR2FFAR1AKR1B1GBA1 | |
| SCHEMBL9262231 | 0.74 | PPARG (0.46) | GSK3AGSK3BAXLFLT3MERTK | |
| SCHEMBL9262125 | 0.74 | AXL (0.41) | EGLN1ESR2GSK3AGSK3BAXL | |
| SCHEMBL9260186 | 0.73 | PPARG (0.43) | GSK3AGSK3BAXLFLT3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |