Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312739 | 0.94 | PPARG (0.45) | PPARGACHEGSK3AGSK3BESR2 | |
| SCHEMBL9258548 | 0.86 | ESR2 (0.40) | PPARGGSK3AGSK3BESR2 | |
| SCHEMBL9262231 | 0.84 | PPARG (0.46) | PPARGGSK3AGSK3B | |
| SCHEMBL7320243 | 0.83 | PPARG (0.47) | PPARGACHEGSK3AGSK3B | |
| SCHEMBL7319487 | 0.83 | PPARG (0.45) | PPARGACHEGSK3AGSK3B | |
| SCHEMBL9256683 | 0.83 | EGLN1 (0.45) | PPARGGSK3AGSK3BESR2 | |
| SCHEMBL9260186 | 0.81 | PPARG (0.43) | PPARGACHEGSK3AGSK3B | |
| SCHEMBL9264481 | 0.81 | TRPV1 (0.36) | PPARG | |
| SCHEMBL9260088 | 0.81 | PPARG (0.47) | PPARGACHEAGTR1AGTR2GSK3A | |
| SCHEMBL9261174 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |