Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 8/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510581 | 0.79 | NOTUM (0.37) | GSK3BNOTUMBCHEACHEHSD17B3 | |
| SCHEMBL7935767 | 0.71 | NOTUM (0.36) | NOTUMBCHEHSD17B3NOX1 | |
| SCHEMBL4613405 | 0.69 | NOTUM (0.34) | NOTUMBCHEHSD17B3 | |
| SCHEMBL6096618 | 0.69 | NOTUM (0.42) | GSK3BNOTUMBCHEACHEHSD17B3 | |
| SCHEMBL11663903 | 0.68 | KMT2A (0.44) | NOTUMBCHEACHEHSD17B3KDM4E | |
| SCHEMBL8464806 | 0.68 | ALOX15 (0.41) | NOTUMBCHENPC1RAB9ATSHR | |
| SCHEMBL28877548 | 0.68 | NOTUM (0.39) | GSK3BNOTUMBCHEACHEHSD17B3 | |
| SCHEMBL14876492 | 0.67 | BCHE (0.31) | NOTUMBCHEHTR2A | |
| SCHEMBL221834 | 0.67 | KDM1A (0.41) | NOTUMBCHEKDM4EALDH1A1 | |
| SCHEMBL12980392 | 0.67 | KDM1A (0.38) | NOTUMBCHEHSD17B3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442047-A | Process for preparing isepamicin | SCHERING CORPORATION (US) | 1995-08-15 | — | — | US | claimed |