Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272741 | 0.84 | MEN1 (0.45) | MEN1KMT2AHTTIKBKBSLC2A1 | |
| SCHEMBL9265685 | 0.81 | SLC2A1 (0.62) | MEN1KMT2AHTTIKBKBSLC2A1 | |
| SCHEMBL9264323 | 0.79 | SLC2A1 (0.60) | MEN1KMT2AHTTIKBKBSLC2A1 | |
| SCHEMBL9262778 | 0.78 | TYMP (0.51) | MEN1KMT2ASLC2A1GAAPTGS2 | |
| SCHEMBL3392595 | 0.78 | SLC2A1 (0.48) | MEN1KMT2AIKBKBSLC2A1GAA | |
| SCHEMBL3392710 | 0.78 | SLC2A1 (0.48) | MEN1KMT2AHTTIKBKBSLC2A1 | |
| SCHEMBL9272305 | 0.77 | PDGFRA (0.50) | MEN1KMT2AHTTSLC2A1GAA | |
| SCHEMBL9266330 | 0.77 | TYMP (0.50) | MEN1KMT2ASLC2A1GAAPTGS2 | |
| SCHEMBL9271084 | 0.77 | MEN1 (0.47) | MEN1KMT2AHTTIKBKBAHR | |
| SCHEMBL9270359 | 0.73 | SLC2A1 (0.78) | MEN1KMT2AHTTIKBKBSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |