Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264323 | 0.98 | SLC2A1 (0.60) | SLC2A1BRD4LMNAGAAMAPT | |
| SCHEMBL9270359 | 0.91 | SLC2A1 (0.78) | SLC2A1BRD4LMNAGAAMAPT | |
| SCHEMBL9282992 | 0.89 | SLC2A1 (0.52) | SLC2A1BRD4GAAMEN1KMT2A | |
| SCHEMBL9260938 | 0.89 | SLC2A1 (0.52) | SLC2A1BRD4GAAMAPTMEN1 | |
| SCHEMBL3392595 | 0.86 | SLC2A1 (0.48) | SLC2A1BRD4GAAMAPTIKBKB | |
| SCHEMBL9262778 | 0.86 | TYMP (0.51) | SLC2A1GAAMEN1KMT2APTGS2 | |
| SCHEMBL3392710 | 0.86 | SLC2A1 (0.48) | SLC2A1BRD4LMNAGAAMAPT | |
| SCHEMBL9272305 | 0.85 | PDGFRA (0.50) | SLC2A1BRD4LMNAGAAMAPT | |
| SCHEMBL9266330 | 0.84 | TYMP (0.50) | SLC2A1GAAMEN1KMT2APTGS2 | |
| SCHEMBL4478739 | 0.83 | SLC2A1 (0.47) | SLC2A1BRD4GAAMAPTIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |