Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 7/20 | 0.46 |
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255130 | 0.90 | USP2 (0.39) | USP2ALDH1A1ENPP1CYP3A4SLC16A3 | |
| SCHEMBL9256744 | 0.81 | SLC33A1 (0.38) | ENPP1 | |
| SCHEMBL9253560 | 0.81 | SLC33A1 (0.36) | ENPP1 | |
| SCHEMBL7310843 | 0.81 | SLC33A1 (0.41) | — | |
| SCHEMBL9254444 | 0.81 | SLC33A1 (0.48) | — | |
| SCHEMBL8314256 | 0.80 | SLC33A1 (0.46) | — | |
| SCHEMBL9257779 | 0.80 | SLC33A1 (0.46) | — | |
| SCHEMBL9256912 | 0.80 | SLC33A1 (0.46) | — | |
| SCHEMBL9253961 | 0.80 | SLC33A1 (0.46) | MBOAT4 | |
| SCHEMBL9258857 | 0.80 | SLC33A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |