Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577687 | 0.95 | SOAT1 (0.75) | SOAT1PPARGPPARAPPARDHRH3 | |
| SCHEMBL9260761 | 0.92 | SOAT1 (0.70) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL9257327 | 0.88 | SOAT1 (0.86) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL10587602 | 0.88 | SOAT1 (0.86) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL9260772 | 0.88 | SOAT1 (0.70) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL8767865 | 0.87 | SOAT1 (0.64) | SOAT1PPARGPPARAPPARDHRH3 | |
| SCHEMBL9255485 | 0.86 | PPARG (0.68) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL9784440 | 0.85 | SOAT1 (0.81) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL9784466 | 0.85 | SOAT1 (0.68) | SOAT1PPARGPPARAPPARDHRH3 | |
| SCHEMBL9784436 | 0.84 | SOAT1 (0.59) | SOAT1PPARGPPARAPPARDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422373-A | An alkoxybenzyl-alkylene-arylurea anticholesterol, antilipemic agents and enzyme inhibitors | BURROUGHS WELLCOME CO. (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0550568-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006075-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |