Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.68 |
| ▸ | PPARA | Q07869 | 4/20 | 0.68 |
| ▸ | PPARD | Q03181 | 2/20 | 0.61 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257035 | 0.86 | SOAT1 (0.69) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL9253022 | 0.85 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL9260761 | 0.85 | SOAT1 (0.70) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL9260772 | 0.83 | SOAT1 (0.70) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL9577687 | 0.82 | SOAT1 (0.75) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL28023966 | 0.82 | PPARG (0.72) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL8159724 | 0.81 | PPARA (1.00) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL6060924 | 0.79 | PPARG (1.00) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL29376860 | 0.79 | PPARG (1.00) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL8768837 | 0.79 | PPARG (0.82) | PPARGPPARAPPARDSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422373-A | An alkoxybenzyl-alkylene-arylurea anticholesterol, antilipemic agents and enzyme inhibitors | BURROUGHS WELLCOME CO. (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0550568-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006075-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |