⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3896192 | 0.97 | — | — | |
| SCHEMBL3322626 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL19501699 | 0.67 | — | — | |
| SCHEMBL2156910 | 0.65 | — | — | |
| SCHEMBL19519266 | 0.63 | — | — | |
| Diethylamine SCHEMBL28176759 | 0.62 | — | — | |
| Fluoride SCHEMBL16266752 | 0.62 | TP53 (0.33) | — | |
| SCHEMBL1900698 | 0.59 | — | — | |
| SCHEMBL13538948 | 0.59 | — | — | |
| SCHEMBL33233 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2540320-A1 | LEPTOMYCIN DERIVATIVES | SANOFI (FR) | 2013-01-02 | — | — | EP | disclosed |
| EP-2032172-B1 | LEPTOMYCIN DERIVATIVES | SANOFI SA (FR) | 2012-06-06 | — | — | EP | disclosed |
| US-20110002947-A1 | LEPTOMYCIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | US | disclosed |
| US-7816543-B2 | Leptomycin derivatives | SANOFI-AVENTIS (FR) | 2010-10-19 | — | — | US | disclosed |
| US-20090182038-A1 | Leptomycin Derivatives | SANOFI-AVENTIS (FR) | 2009-07-16 | — | — | US | disclosed |
| EP-2032172-A2 | LEPTOMYCIN DERIVATIVES | Sanofi-Aventis (FR) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007144709-A2 | LEPTOMYCIN DERIVATIVES | SANOFI-AVENTIS (FR) | 2007-12-21 | — | — | WO | disclosed |
| EP-1864682-A1 | Leptomycin derivatives | Sanofi-Aventis (FR) | 2007-12-12 | — | — | EP | disclosed |
| EP-0375422-B1 | Composition and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine | BEHRINGWERKE AG (DE) | 1996-07-03 | — | — | EP | disclosed |
| US-5328828-A | Immunoassay for amphetamines with antibodies for conjugation and enzymes | SYNTEX (U.S.A.) INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5135863-A | Immunoassay; drug abuse | SYNTEX (U.S.A.) INC. (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0375422-A2 | Composition and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine | BEHRINGWERKE Aktiengesellschaft (DE) | 1990-06-27 | — | — | EP | disclosed |