Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.77 |
| ▸ | PTPRC | P08575 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.57 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.57 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303600 | 0.94 | S100A4 (0.81) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL11317413 | 0.92 | S100A4 (0.78) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL2347136 | 0.91 | S100A4 (0.84) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL11210972 | 0.90 | S100A4 (0.75) | S100A4PTPRCMAPTRECQLKMT2A | |
| Anthraquinone SCHEMBL27518707 | 0.90 | S100A4 (0.79) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL161290 | 0.90 | S100A4 (0.73) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL6364877 | 0.90 | S100A4 (0.79) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL32670296 | 0.90 | S100A4 (0.79) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL28651375 | 0.87 | S100A4 (0.92) | S100A4PTPRCMAPTRECQLKMT2A | |
| SCHEMBL2599501 | 0.87 | S100A4 (1.00) | S100A4PTPRCMAPTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102382109-A | Preparation method of 1,8-dinitro-9-fluorenone | SUZHOU BEC BIOLOGY TECHNOLOGY CO LTD | 2012-03-21 | — | — | CN | disclosed |
| CN-102382109-A | Preparation method of 1,8-dinitro-9-fluorenone | SUZHOU BEC BIOLOGY TECHNOLOGY CO LTD | 2012-03-21 | — | — | CN | disclosed |
| US-5434264-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
| US-5300642-A | α, α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0311010-B1 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | DU PONT MERCK PHARMA (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0532054-A1 | Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5173489-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0311010-A2 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |