Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802073 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL28138500 | 0.83 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL20166110 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL4918301 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAL3MBTL1CYP2C9 | |
| SCHEMBL9554785 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL28488318 | 0.80 | MEN1 (0.44) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL5696562 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL20166020 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL28835766 | 0.79 | HSD17B10 (0.45) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB | |
| SCHEMBL28487387 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HSD17B10LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995032192-A1 | AROMATIC AMINE SUBSTITUTED BRIDGED NITROGEN AND SULFUR DONOR ATOM LIGANDS FOR IMAGING | NEORX CORPORATION (US) | 1995-11-30 | — | — | WO | disclosed |