SCHEMBL9257545

SCHEMBL9257545

C=CC(=O)NC(OC)C(=O)OC(C)C

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
ACACB O00763 2/20 0.35
TGM2 P21980 1/20 0.32
CYP2C19 P33261 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451042 0.84 TSHR (0.52) TSHRACACBTGM2CYP2C19ALDH1A1
SCHEMBL21368256 0.81 TSHR (0.54) TSHRACACBTGM2CYP2C19HCAR2
SCHEMBL9286940 0.80 TSHR (0.44) TSHRACACBTGM2CYP2C19ALDH1A1
Methoxymethane SCHEMBL9257547 0.80 TSHR (0.48) TSHRACACBTGM2CYP2C19
SCHEMBL21367997 0.78 TSHR (0.50) TSHRACACBCYP2C19HCAR2ALDH1A1
SCHEMBL9257605 0.78 TSHR (0.45) TSHRACACBTGM2ALDH1A1MAPK1
SCHEMBL9254769 0.76 TSHR (0.44) TSHRTGM2CYP2C19ALDH1A1
SCHEMBL363847 0.76 TSHR (0.52) TSHRACACBTGM2CYP2C19ALDH1A1
SCHEMBL9257599 0.76 TSHR (0.44) TSHRACACBTGM2ALDH1A1MAPK1
SCHEMBL1472003 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5478688-A Liquid developer compositions with charge adjuvants of a copolymer of an alky acrylamidoglycolate alkyl ether and an alkenylester XEROX CORPORATION (US) 1995-12-26 US disclosed