SCHEMBL451042

SCHEMBL451042

C=CC(=O)NC(OC)C(=O)OC

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
TGM2 P21980 2/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACACB O00763 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9254769 0.91 TSHR (0.44) TSHRTGM2CYP2C19ALDH1A1
SCHEMBL9257605 0.84 TSHR (0.45) TSHRTGM2SMN1; SMN2ALDH1A1MAPK1
SCHEMBL9257545 0.84 TSHR (0.50) TSHRTGM2CYP2C19ALDH1A1MAPK1
SCHEMBL9286940 0.83 TSHR (0.44) TSHRTGM2CYP2C19SMN1; SMN2ALDH1A1
SCHEMBL363847 0.83 TSHR (0.52) TSHRTGM2CYP2C19ALDH1A1MAPK1
SCHEMBL8041733 0.82 TSHR (0.47) TSHRTGM2CYP2C19SMN1; SMN2ALDH1A1
SCHEMBL9228834 0.81 TSHR (0.50) TSHRTGM2CYP2C19ALDH1A1MAPK1
SCHEMBL9262683 0.80 TSHR (0.45) TSHRTGM2CYP2C19ALDH1A1MAPK1
SCHEMBL3914392 0.80 TSHR (0.54) TSHRTGM2CYP2C19SMN1; SMN2ALDH1A1
SCHEMBL9000784 0.79 TSHR (0.44) TSHRTGM2CYP2C19ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113845569-B Synthetic method of pasireotide intermediate 浙江湃肽生物有限公司南京分公司 2022-02-18 CN claimed
CN-113845569-A Synthetic method of pasireotide intermediate 浙江湃肽生物有限公司南京分公司 2021-12-28 CN claimed
CN-112030314-B Anti-fouling and good-weather-resistance antistatic functional fiber and application thereof 安徽美湖新材料科技有限公司 2021-11-23 CN claimed
CN-111778615-B Preparation method of antistatic woven fabric capable of absorbing sweat and removing dirt 深圳市健力达纺织品有限公司 2021-10-22 CN claimed
CN-110528141-B Antistatic textile fabric and preparation method thereof 无锡兴之盛针织有限公司 2021-01-26 CN claimed
CN-112030314-A Anti-fouling and good-weather-resistance antistatic functional fiber and application thereof 朱建余 2020-12-04 CN claimed
CN-111778615-A Preparation method of antistatic woven fabric capable of absorbing sweat and removing dirt 朱建余 2020-10-16 CN claimed
CN-110528141-A Antistatic textile fabric and preparation method thereof ZHU JIANYU 2019-12-03 CN claimed
EP-1687475-B1 THREADS, FIBRES AND FILAMENTS FOR WEAVING WITHOUT SIZING RHODIA INDUSTRIAL YARNS AG (CH) 2010-11-24 EP claimed
US-20070270065-A1 Threads, Fibres and Filaments for Weaving Without Sizing NEXIS FIBERS AG (CH) 2007-11-22 US claimed
EP-0877765-A1 GRAFT COPOLYMERS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAID COPOLYMERS, AND USE THEREOF FOR PREPARING PIGMENT DISPERSIONS IN AQUEOUS AND/OR ORGANIC MEDIA LES PEINTURES JEFCO (FR) 1998-11-18 EP claimed
WO-1997028200-A1 GRAFT COPOLYMERS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAID COPOLYMERS, AND USE THEREOF FOR PREPARING PIGMENT DISPERSIONS IN AQUEOUS AND/OR ORGANIC MEDIA LES PEINTURES JEFCO (FR) 1997-08-07 WO claimed
US-5651648-A Method for reducing ceramic tool wear and friction in machining/cutting applications VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1997-07-29 US claimed
US-5407601-A Applying lubricating composition containing methyl 2-acrylamido-2-methoxy acetate dissolved or dispersed in carrier fluid of mineral oil, hydrocarbon fuel, synthetic oil or hexadecane CENTER FOR INNOVATIVE TECHNOLOGY (US) 1995-04-18 US claimed
EP-0644061-A2 Antistatic subbing layer for slipping layer in dye-donor element used in thermal dye transfer EASTMAN KODAK COMPANY (US) 1995-03-22 EP claimed
US-5336659-A Polymer blend EASTMAN KODAK COMPANY (US) 1994-08-09 US claimed
US-5147571-A Mixing ethylene polymer with methacrylamido glycolate methyl ether, reacting product with amine TEXACO INC. (US) 1992-09-15 US claimed
EP-0315533-B1 PURE CRYSTALLINE METHYL 2-ACRYLAMINO 2-METHOXY ACETATE AND PROCESS FOR ITS PREPARATION SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) 1992-09-02 EP claimed
WO-1992007923-A1 COMPOSITIONS FOR REDUCING WEAR ON CERAMIC SURFACES VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) 1992-05-14 WO claimed
US-4960923-A REACTING ACRYLAMIDOGLYCOLIC ACID WITH METHANOL SOCIETE FRANCAISE HOECHST (FR) 1990-10-02 US claimed