Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260294 | 0.96 | NPC1 (0.57) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9398464 | 0.92 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9396960 | 0.91 | NPC1 (0.57) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL21084486 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL9855583 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL12299687 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL13325825 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL21084423 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL21124189 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 | |
| SCHEMBL4171854 | 0.89 | LMNA (0.69) | SMN1; SMN2LMNANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385693-A | Having rapid response and low phase transition temperature | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0357372-B1 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL CO (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5264151-A | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |