Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 7/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067987 | 0.86 | USP2 (0.48) | TP53MAPTLMNAIDH1POLB | |
| SCHEMBL6958441 | 0.76 | TP53 (0.36) | TP53MAPTLMNAALDH1A1 | |
| SCHEMBL6902727 | 0.74 | IDH1 (0.44) | LMNAIDH1ALDH1A1 | |
| SCHEMBL14830721 | 0.73 | MAPK1 (0.38) | TP53IDH1ALDH1A1 | |
| SCHEMBL9274384 | 0.72 | MAPT (0.46) | MAPTLMNAALDH1A1 | |
| SCHEMBL10308853 | 0.72 | IDH1 (0.48) | IDH1 | |
| SCHEMBL8475478 | 0.72 | IDH1 (0.51) | IDH1ALDH1A1MTOR | |
| SCHEMBL8475475 | 0.72 | IDH1 (0.51) | IDH1ALDH1A1MTOR | |
| SCHEMBL28613647 | 0.72 | TP53 (0.35) | TP53LMNAIDH1ALDH1A1 | |
| SCHEMBL27992730 | 0.70 | USP2 (0.44) | LMNAPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632802-A1 | NEW ALKYLATING REAGENT, PROCESS FOR PREPARING THE SAME AND ITS USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-01-11 | — | — | EP | claimed |
| WO-1993019043-A1 | NEW ALKYLATING REAGENT, PROCESS FOR PREPARING THE SAME AND ITS USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-30 | — | — | WO | claimed |