Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781874 | 0.74 | MAPT (0.70) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL9257560 | 0.72 | TP53 (0.48) | MAPTALDH1A1LMNA | |
| SCHEMBL9274386 | 0.68 | MAPT (0.47) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL6958441 | 0.67 | TP53 (0.36) | MAPTALDH1A1LMNA | |
| SCHEMBL14438077 | 0.67 | MAPT (0.74) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL12282092 | 0.66 | MAPT (0.76) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL13448477 | 0.66 | KMT2A (0.57) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL9274379 | 0.65 | MAPT (0.51) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL30528252 | 0.65 | MAPT (0.86) | MAPTALDH1A1HTR1AHTR7LMNA | |
| SCHEMBL7840682 | 0.64 | MAPT (0.72) | MAPTALDH1A1HTR1AHTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |