Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | CPA3 | P15088 | 3/20 | 0.41 |
| ▸ | CPA1 | P15085 | 7/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263089 | 0.88 | KMT2A (0.52) | CYP1A2FOLH1CPA3CPA1ALDH1A1 | |
| SCHEMBL9263093 | 0.88 | KMT2A (0.52) | CYP1A2FOLH1CPA3CPA1ALDH1A1 | |
| SCHEMBL9254625 | 0.87 | FOLH1 (0.41) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL9254630 | 0.87 | FOLH1 (0.41) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL9262360 | 0.86 | CYP1A2 (0.41) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL9260415 | 0.84 | HSD17B10 (0.50) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL9287474 | 0.84 | HSD17B10 (0.50) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL9260958 | 0.83 | CYP1A2 (0.42) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL7163448 | 0.83 | SMN1; SMN2 (0.48) | CYP1A2FOLH1CPA3CPA1CPB1 | |
| SCHEMBL8670521 | 0.83 | SMN1; SMN2 (0.48) | CYP1A2FOLH1CPA3CPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |