Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518743 | 0.93 | NR1H2 (0.66) | ESR2NR1H2NPC1RAB9AESR1 | |
| SCHEMBL2307305 | 0.85 | ESR2 (0.60) | ESR2NR1H2NPC1RAB9AESR1 | |
| SCHEMBL7277087 | 0.83 | ESR2 (0.57) | ESR2NR1H2NPC1RAB9AESR1 | |
| SCHEMBL26596774 | 0.83 | ESR2 (0.57) | ESR2NR1H2NPC1RAB9AESR1 | |
| SCHEMBL3892320 | 0.82 | ESR2 (0.56) | ESR2NR1H2NPC1RAB9AGPR119 | |
| SCHEMBL4039631 | 0.82 | ESR2 (0.56) | ESR2NR1H2NPC1RAB9AESR1 | |
| SCHEMBL7285018 | 0.82 | NR1H2 (0.58) | ESR2NR1H2NPC1RAB9AESR1 | |
| SCHEMBL31281068 | 0.82 | ESR2 (0.59) | ESR2NR1H2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12608362 | 0.82 | ESR2 (0.59) | ESR2NR1H2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4917789 | 0.81 | ESR2 (0.55) | ESR2NR1H2NPC1RAB9AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |