Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247300 | 0.78 | CA2 (0.49) | CA2CA4CA1CA12CA7 | |
| SCHEMBL9251357 | 0.77 | CA2 (0.39) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9253408 | 0.67 | CA2 (0.43) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9428734 | 0.63 | CA2 (0.52) | CA2 | |
| SCHEMBL9429942 | 0.62 | CA2 (0.49) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9429933 | 0.62 | CA2 (0.49) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9429939 | 0.62 | CA2 (0.49) | CA2CA4CA1CA12CA3 | |
| SCHEMBL8705943 | 0.61 | CA2 (0.71) | CA2CA4CA1CA12CA3 | |
| SCHEMBL9429842 | 0.61 | CA2 (0.56) | CA2 | |
| SCHEMBL9429846 | 0.61 | CA2 (0.56) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464831-A | Treatment of glaucoma | ALCON LABORATORIES, INC. (US) | 1995-11-07 | — | — | US | disclosed |