Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | ITGAL | P20701 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9156812 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL15688496 | 0.82 | TDP1 (0.43) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL5540570 | 0.82 | TDP1 (0.47) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL15688498 | 0.82 | TDP1 (0.43) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL5540574 | 0.82 | TDP1 (0.47) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL12500455 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL5540599 | 0.80 | TDP1 (0.48) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL5540601 | 0.80 | TDP1 (0.48) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL10324416 | 0.80 | PDE5A (0.44) | ALDH1A1MAPTKDM4EGAAL3MBTL1 | |
| SCHEMBL3436152 | 0.80 | PDE5A (0.44) | ALDH1A1MAPTKDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447954-A | Antilipidemic agents | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-09-05 | — | — | US | disclosed |
| WO-1993022304-A1 | PHENYLDERIVATE AS INHIBITORS OF ATP CITRATE LYASE | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | disclosed |