Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382806 | 0.93 | NPC1 (0.35) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL7787074 | 0.90 | CYP1A2 (0.38) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL9268361 | 0.89 | NPC1 (0.36) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL9266221 | 0.89 | HSP90AA1 (0.36) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL9254528 | 0.89 | NPC1 (0.33) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL7785455 | 0.87 | NPC1 (0.35) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL24236676 | 0.86 | NPC1 (0.35) | NPC1RAB9AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL22164133 | 0.83 | NPC1 (0.41) | NPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL30631662 | 0.83 | NPC1 (0.41) | NPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL22184105 | 0.82 | NPC1 (0.45) | NPC1RAB9ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | claimed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | claimed |
| US-5410071-A | Sulfiding with a thiophenolic compound or a thiophenolate in a polar solvent to form a stabilizers for polyphenylene sulfide against UV radiation | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5319091-A | Contacting sulfur-containing aromatic compound with hydroxyphenylbenzotriazole derivative in presence of polar organic compound, oxidizing formed aryl sulfide derivative to sulfone, sulfoxide or mixtures | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |