Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258027 | 1.00 | AGTR1 (0.35) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL9252048 | 0.82 | AGTR1 (0.41) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL9258021 | 0.81 | AGTR1 (0.34) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL9248296 | 0.80 | AGTR1 (0.48) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL9541024 | 0.79 | AGTR1 (0.47) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL683867 | 0.78 | AGTR1 (0.51) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL683444 | 0.77 | AGTR1 (0.50) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL683512 | 0.77 | AGTR1 (0.50) | AGTR1LTB4R2AGTR2 | |
| SCHEMBL9366716 | 0.76 | AGTR1 (0.31) | AGTR1LTB4R2 | |
| SCHEMBL7827025 | 0.75 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424450-A | Angiotensin II receptor blocking imidazolinone derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1993004045-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |